I posted this research paper on my facebook page, but as many of you don't do facebook I though it would be best to post it here.
You may have heard about this study on the news a few months ago. As an area I like to specialise in it's fantasic stuff to see. However, we do need to be careful about what we take from these results - 600 calorie diets are going to be very tough to do, and calories need to come from the right sources - so that vitamins and minerals are still being put into the body. I DO NOT recommend this protocol to anyone without medical supervision! As the authors state, further research is needed in the long term effects of such a drastic nutritional protocol.
The study invesitgated whether an energy restricted diet
had an effect on the biochemical signs of type 2 diabetes. Researchers
wanted to see if diet could reverse the resistance of the body's cells
to the actions of insulin, and prevent progressive decline in function of beta cells.
The research was non-randomised in 11 people with type 2 diabetes. There was no control group.
The idea was that a sudden negative energy balance would have a profound effect on metabolism, decreasing concentrations of fatty acids which are said to inhibit the funciton of beta cells. An expected decrease would improve insulin function.
All diabetes medication was withdrawn for the study. Each participant had 600 calories per day. At 8 weeks participants returned to normal eating.
At the end of 1 week - blood sugar levels normalised. Production of glucose from the liver decreased and sensitivity to insulin improved from 43% to 74%. By week 8 the fatty acid content of the liver had fallen from 12.8% to 2.9% whiles levels in the pancreas fell from 8%to 6.2%. Average weight loss was 15.3kg. 4 weeks after the cesation of the diet, weight increaed by 3.1kg but decreases in triacylglycerol content of the liver and pancreas were maintained.
The research was non-randomised in 11 people with type 2 diabetes. There was no control group.
The idea was that a sudden negative energy balance would have a profound effect on metabolism, decreasing concentrations of fatty acids which are said to inhibit the funciton of beta cells. An expected decrease would improve insulin function.
All diabetes medication was withdrawn for the study. Each participant had 600 calories per day. At 8 weeks participants returned to normal eating.
At the end of 1 week - blood sugar levels normalised. Production of glucose from the liver decreased and sensitivity to insulin improved from 43% to 74%. By week 8 the fatty acid content of the liver had fallen from 12.8% to 2.9% whiles levels in the pancreas fell from 8%to 6.2%. Average weight loss was 15.3kg. 4 weeks after the cesation of the diet, weight increaed by 3.1kg but decreases in triacylglycerol content of the liver and pancreas were maintained.
3 months post intervention, 7 of the 11 were still free of Type 2 diabetes. An article has also been published by one participant who was still free of the disease 18 months later.
You can download the whole paper here
No comments:
Post a Comment